Combination Therapy Transforms HIV Treatment
In 1996, triple-drug antiretroviral therapy, often called highly active antiretroviral therapy or HAART, showed that HIV replication could be durably suppressed. The breakthrough combined existing drugs with new protease inhibitors, changing the clinical prospects for many people living with HIV.
Impact & Significance
Combination therapy helped transform HIV from an almost universally fatal diagnosis into a manageable long-term condition for people with access to treatment, reshaping activism, care, prevention and public expectations.
Reference Record
- Date
- 1996
- Era
- 1990-1999
- Sources
- 1
Editorially reviewed — reviewed · last reviewed 2026-06-01.